[PDF] The Modification of Xa-ATIII-Heparin Dynamics by Protamine Sulfate …
Heparin promotes the formation of 1∘ FXaα-ATIII and FXaβ-ATIII complexes from the free enzymes and antithrombin III. It further stimulates the transformations of the 1∘ complexes into the corresponding 3∘ complexes. Additionally, it stimulates the degradation of the 1∘ FXaα-ATIII and FXaβ-ATIII complexes into free FXaα, FXaβ and ATIIIM. Protamine sulfate (PS) stimulates the ...